Why Ryniant
What makes it different
Orchestration
One instruction. The whole platform.
Give it a goal and it drives every part of the system to finish the job. It plans the route, validates it, checks your inventory, sources what is missing, builds the quote, and updates the project. It pauses and asks before anything leaves your lab.
Reasoning
It thinks for itself.
It raises what a senior chemist would raise, shows the precedent behind the claim, and asks before it tests. Then it runs the test and tells you what the result means.
Strategy
Plans like a chemist.
It reasons about the whole molecule first. Routes come back convergent, stereochemically correct, and sequenced to avoid dead ends. Not a greedy search.
Creativity
Novel by design.
A frontier AI proposes elegant disconnections for molecules that literature tools return nothing for. Every step is verified as real chemistry before you see it.
Memory
Learns from your chemistry.
Drop in your past routes and your papers. It reads them and plans novel targets by analogy to work you have already done. Every route you run makes the next one sharper.
Feasibility
Know which conditions will fire.
Before the bench, Ryniant reads your own notebook, including the reactions that failed, and tells you which conditions to run and which to skip. Screen the two your history supports instead of five run blind. Fewer wells, less material, less time.
Operations
Sourcing and quoting, solved.
Every reagent priced, every vendor found, single-supplier risk and import delays estimated before they break a deadline. A client-ready quote from the same route. Days of back-and-forth, gone.
How it works
Under the hood
01
Put in a molecule, and a brief.
Paste a SMILES, type a name, or draw the structure, including novel molecules with no published route. Then brief it the way you would brief a colleague. "Plan a carbon-14 route. Introduce the label in the final three steps, on a metabolically stable carbon, from a commercial ¹⁴C building block. Keep radiochemical yield high and no chromatography on the labelled intermediates." It parses that into a real synthesis brief and plans against it. Connect your inventory and equipment so every route fits your lab from the start.
02
Give it your chemistry.
Drop in your past routes, your internal syntheses, your papers. It reads them, pulls out the reactions, and plans the novel target by analogy to work you have already done, citing the exact route and step it reasoned from. This is how chemists actually work a new molecule.
03
Strategy before the route.
This is the creative engine. Most tools generate a route before they plan a strategy, so on a novel molecule they return long linear sequences, odd disconnections, and reagents you cannot source. Ryniant plans the disconnection strategy first, optimizing for convergence and yield the way a chemist would, then builds and checks the route around it. Every strategy is shown to you, and every chemistry assumption is cited and tested against hard chemical and thermodynamic checks. Fewer strange disconnections, fewer needless protecting groups, shorter longest linear sequences.
04
Direct the exploration.
Tell it how deep to go. Explore five disconnections at one intermediate, three at another, four at a third. It runs every branch, validates each, and hands back an efficacy report per sub-route, ranked. Every route stays interactive. Click the final molecule for a different full route. Click any intermediate for another way to make just that piece.
05
It thinks for itself, and asks.
While it works, it raises what a senior chemist would raise. "A Negishi at this intermediate should out-yield the Suzuki and cost less." It shows the precedent behind the claim, asks before it tests, runs the test, and tells you what the result means. You approve, edit, or reject.
06
Know which conditions will fire, before the bench.
Chemists screen four or five conditions in parallel on an uncertain step because they cannot tell which one will fire. Ryniant reads your own notebook for the closest reactions you have run, including the ones that failed, and gives each condition a read: start here, also supported, or skip. You run the two your history backs instead of five run blind. That is real material, time, and cost saved on every uncertain step, and every call cites the exact experiment it came from. It informs your chemists' judgment, it does not replace it, and it runs on your private data.
07
See the evidence.
Real citations on precedented steps, honest labeling on the novel ones, and every validation check shown. Built for chemists who verify.
08
Source it and quote it.
From the same route: a bill of materials with live supplier pricing, lead-time and import-delay estimates, and a labor estimate per step, summed into a client-ready quote. Estimates based on current commerce conditions.
09
One instruction. The whole platform.
The agent does not stop at the route. From a single instruction it moves across the entire system: it creates the client request, plans and validates the route, checks your inventory, sources what is missing, drafts the supplier emails, builds the quote, and updates the project. You watch every step happen in the side panel, and it stops and asks you before anything leaves your lab.
What You Get Back
Pre-validated, not raw output.
Every step is scored, optimized, and checked before you see it. Weak conditions are replaced and better alternatives are proposed. You get the best version, not a starting point.
Costs against your shelf.
Live supplier pricing at your purchase quantities. Anything already in your inventory is zeroed out. You see what you actually need to spend.
Bench-ready protocol.
Step-by-step instructions with quantities, conditions, and times. Hazardous intermediates flagged with GHS classifications. Ready for the bench or the client.
Built To Be Trusted
Every route shows its work.
Nothing is a black box. Real published precedent where it exists, honest labels where it does not, and calibrated confidence on every step. The strategy is explained in plain terms, and every validation check is visible. This is the tool a chemist who lives in the literature can actually trust.
Who It Is For
Contract Chemistry Labs
Route packages that already fit your equipment and inventory, with sourcing and quoting built in. Win the RFQ race on speed.
Medicinal Chemists
The best route for any candidate in minutes, pre-optimized on real data instead of literature guesses. Spend your time on the chemistry.
Discovery Program Leaders
Synthesis cost and feasibility for every molecule in the pipeline, before you commit a single reaction.
One scientist. A dozen workflows, running at once.
Because everything around the chemistry runs itself, nothing waits in line. While one route is scoring, the next twelve are already moving.